
OATPs
Organic Anion Transporting
Polypeptides
OCTs
Organic Cation
Transporters
NTCPs
Na+-taurocholate co-transporting Polypeptides
OATs
Organic Anion
Transporters
ABTs (IBAT, ISBT)
Apical sodium-dependent Bile Acid Transporters
Brief Summary
The knowledge of drug affinity and drug-drug interaction (DDI) to uptake and efflux transporters is a fundamental requirement in drug development, recommended by the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA).
Primacyt utilizes HEK-293 cells, each cell line is stable transfected with one uptake transporter protein. Our assays deliver information on the uptake, efflux and inhibitory potential of drugs and other compounds.
OATPs
Organic Anion Transporting
Polypeptides
OCTs
Organic Cation
Transporters
NTCPs
Na+-taurocholate co-transporting Polypeptides
OATs
Organic Anion
Transporters
ABTs (IBAT, ISBT)
Apical sodium-dependent Bile Acid Transporters
Brief Summary
The knowledge of drug affinity and drug-drug interaction (DDI) to uptake and efflux transporters is a fundamental requirement in drug development, recommended by the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA).
Primacyt utilizes HEK-293 cells, each cell line is stable transfected with one uptake transporter protein. Our assays deliver information on the uptake, efflux and inhibitory potential of drugs and other compounds.